Scheduled oral analgesics and the need for opiates in children following partial dorsal rhizotomy

J Neurosurg. 2007 Jun;106(6 Suppl):439-40. doi: 10.3171/ped.2007.106.6.439.

Abstract

Object: Postoperative epidural morphine is commonly used to control pain in children following dorsal rhizotomy for spasticity. The authors report their experience in using a regimen of scheduled minor analgesic drugs to manage postoperative pain, with the goal of avoiding opiate use following a spinal intradural procedure.

Methods: Postoperative pain scores were analyzed in a group of 22 children who underwent a partial dorsal rhizotomy. According to a preestablished standard regimen for postoperative pain control after dorsal rhizotomy, in each patient an intraoperative epidural catheter was placed for the potential infusion of postoperative morphine. Additionally, this cohort underwent a scheduled regimen of acetaminophen (10 mg/kg) and ibuprofen (10 mg/kg), alternating every 2 hours. For comparison, a retrospective chart review was performed in 20 patients with rhizotomies completed prior to the use of this oral analgesic protocol. Only one patient received a postoperative dose of morphine epidurally. None of the remaining patients required postoperative epidural morphine for pain control. Pain scores were significantly lower in this group compared with a retrospective review of patients treated according to the standard regimen. Length of hospital stay was shorter in these patients and antiemetic requirements were lower.

Conclusions: A regimen of minor analgesic therapy, when given in alternating doses every 2 hours immediately after partial dorsal rhizotomy for spasticity and throughout hospitalization, significantly reduced postoperative pain scores, hospitalization, and antiemetic requirements in these patients.

MeSH terms

  • Acetaminophen / therapeutic use
  • Administration, Oral
  • Analgesia, Epidural
  • Analgesics / administration & dosage
  • Analgesics / therapeutic use*
  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / therapeutic use*
  • Cerebral Palsy / complications
  • Child
  • Child, Preschool
  • Cohort Studies
  • Drug Administration Schedule
  • Female
  • Health Services Needs and Demand*
  • Humans
  • Ibuprofen / therapeutic use
  • Male
  • Morphine / administration & dosage
  • Morphine / therapeutic use
  • Muscle Spasticity / etiology
  • Muscle Spasticity / surgery*
  • Pain, Postoperative / drug therapy*
  • Retrospective Studies
  • Rhizotomy / methods*

Substances

  • Analgesics
  • Analgesics, Opioid
  • Acetaminophen
  • Morphine
  • Ibuprofen