Stent-grafting of the thoracic aorta: feasibility and early results in acute and chronic lesions

J Cardiovasc Med (Hagerstown). 2007 Jul;8(7):504-10. doi: 10.2459/01.JCM.0000278446.04613.fc.

Abstract

Background and aims: Conventional surgery of the thoracic aorta is frequently associated with significant mortality and morbidity. Here we present treatment of surgical pathologies of the thoracic aorta using a less invasive endovascular approach.

Methods: From January 2000 to May 2004, 51 patients (mean age 62.7 +/- 12.8 years, 36 men) underwent endovascular repair of thoracic aortic lesions in our institution. All patients underwent computed tomography scan at discharge, 6 and 12 months and annually thereafter. Clinical follow-up was carried out by outpatient clinic visit or by telephone contact with the patients or their referring physicians. Mean follow-up was 15.8 months.

Results: The 30-day mortality rate was 3.8%, one death in the group of chronic (1.9%) and one in the group of acute lesion (1.9%). The survival rate in the follow-up period was 92.4% at 6 months. Computed tomography angiography confirmed exclusion of the lesion in 25 out of 27 chronic patients, whereas type I and II endoleaks were detected in two patients treated with a secondary procedure. In addition, two patients with an acute type B aortic dissection presented with early endoleaks. The overall rate of complications was 10%. No other endoleaks or deaths were observed at later follow-up.

Conclusions: The early and mid-term results of endovascular stent-grafting for the treatment of chronic and acute thoracic aortic diseases showed a good outcome and low rate of complications. Stent-grafting of the thoracic aorta is still an investigational procedure that needs further validation.

MeSH terms

  • Acute Disease
  • Adult
  • Aged
  • Aorta, Thoracic / injuries
  • Aorta, Thoracic / pathology
  • Aorta, Thoracic / surgery*
  • Aortic Diseases / mortality
  • Aortic Diseases / pathology
  • Aortic Diseases / surgery*
  • Aortic Dissection / pathology
  • Aortic Dissection / surgery
  • Blood Vessel Prosthesis Implantation / adverse effects
  • Blood Vessel Prosthesis*
  • Chronic Disease
  • Coronary Artery Disease / complications
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Radiography, Interventional
  • Stents*
  • Treatment Outcome
  • Ulcer / etiology
  • Ulcer / pathology
  • Ulcer / surgery
  • Ultrasonography, Interventional