Abstract
The integration of tail-anchored membrane proteins at the endoplasmic reticulum occurs via a specialised ATP-dependent pathway, but the cytosolic factors involved have proven elusive. A novel ATPase that mediates this process has now been identified.
MeSH terms
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Adenosine Triphosphatases / metabolism
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Adenosine Triphosphate / metabolism*
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Biological Transport
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Cytosol / metabolism
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Endoplasmic Reticulum / metabolism*
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Endoplasmic Reticulum / ultrastructure
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Gene Expression Regulation, Fungal*
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Membrane Proteins / metabolism*
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Protein Processing, Post-Translational
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Saccharomyces cerevisiae / genetics
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Saccharomyces cerevisiae / metabolism*
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Saccharomyces cerevisiae / ultrastructure
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Saccharomyces cerevisiae Proteins / genetics
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Saccharomyces cerevisiae Proteins / metabolism*
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Signal Transduction
Substances
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Membrane Proteins
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Saccharomyces cerevisiae Proteins
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Adenosine Triphosphate
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Adenosine Triphosphatases