Returning to the pre-antibiotic era in the critically ill: the XDR problem

MeSH terms

• Animals
• Anti-Bacterial Agents / administration & dosage
• Anti-Bacterial Agents / pharmacology
• Anti-Bacterial Agents / therapeutic use*
• Colistin / administration & dosage
• Colistin / pharmacology
• Drug Resistance, Multiple, Bacterial*
• Drug Synergism
• Drug Therapy, Combination
• Gram-Negative Bacterial Infections / drug therapy*
• Humans
• Pseudomonas Infections / drug therapy
• Rats
• Rifampin / administration & dosage
• Rifampin / pharmacology
• Sepsis / drug therapy*
• Treatment Failure