A multimodality approach offers the best chance for treatment of Non-Hodgkin lymphoma. Surgery, radiation therapy, and/or chemotherapy when used in combination offer better response and longterm survival rates. Surgical therapy offers good results in stage I and II according to the Ann Arbor classification. Aim is the excision of the tumor with the removal of lymph nodes. The best treatment in stage III and IV is chemotherapy and radiation followed by surgical tumor reduction. Complications like perforation or bleeding occurred while the patients received either chemotherapy or radiotherapy. Resection of the Non-Hodgkin lymphoma prevented the complications of hemorrhage and perforation associated with chemotherapy and radiation.