Export aspiration system in patients with acute coronary syndrome and visible thrombus provides no substantial benefit

Catheter Cardiovasc Interv. 2007 Jul 1;70(1):35-42. doi: 10.1002/ccd.21065.

Abstract

Objective: A visible thrombus remains a risk factor during percutaneous coronary intervention (PCI).

Methods: Between October 2004 and March 2005, we treated all patients who consecutively presented with acute coronary syndrome + angiographically visible thrombus using the Export Aspiration System (group 1, n = 79). We retrospectively analyzed all consecutive patients who had been treated without a thrombectomy device (group 2, n = 79).

Results: Final TIMI flow 3 or myocardial blush grade (MBG) 3 after completing PCI in group 1 and 2 was seen in 54 patients (68.4%) versus 57 patients (72.2%, P = 0.6) and in 45 patients (57.0%) versus 44 patients (55.7%, P = 0.9), respectively. Final TIMI flow 0 or MBG 0 in group 1 and 2 was observed in eight patients (10.1%) versus four patients (5.1%, P = 0.23) and in 24 patients (30.4%) versus 16 patients (20.3%, P = 0.15), respectively. HISTOLOGIC EVALUATION: Histologic evaluation revealed mostly mixed thrombotic material (83.6%). Microscopic material was seen in 91.8% of cases. MACE: Total MACE rate during hospital stay was 11.4% in both groups.

Conclusion: Using the Export Aspiration System in patients presenting with acute coronary syndrome + visible thrombus provides no substantial benefit.

MeSH terms

  • Acute Disease
  • Adult
  • Aged
  • Aged, 80 and over
  • Angioplasty, Balloon, Coronary* / adverse effects
  • Coronary Angiography
  • Coronary Circulation*
  • Coronary Thrombosis / complications
  • Coronary Thrombosis / diagnostic imaging
  • Coronary Thrombosis / pathology
  • Coronary Thrombosis / physiopathology
  • Coronary Thrombosis / surgery*
  • Female
  • Heart Diseases / etiology
  • Heart Diseases / prevention & control*
  • Humans
  • Male
  • Middle Aged
  • Myocardial Ischemia / complications
  • Myocardial Ischemia / diagnostic imaging
  • Myocardial Ischemia / pathology
  • Myocardial Ischemia / physiopathology
  • Myocardial Ischemia / therapy*
  • Platelet Aggregation Inhibitors / pharmacology
  • Platelet Aggregation Inhibitors / therapeutic use
  • Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors
  • Research Design
  • Retrospective Studies
  • Suction / instrumentation
  • Syndrome
  • Thrombectomy / adverse effects
  • Thrombectomy / instrumentation*
  • Time Factors
  • Treatment Outcome

Substances

  • Platelet Aggregation Inhibitors
  • Platelet Glycoprotein GPIIb-IIIa Complex