Do hyperpolarization-induced proton currents contribute to the pathogenesis of hypokalemic periodic paralysis, a voltage sensor channelopathy?

J Gen Physiol. 2007 Jul;130(1):1-5. doi: 10.1085/jgp.200709834.

Authors

Karin Jurkat-Rott¹, Frank Lehmann-Horn

Affiliation

¹ Institute of Applied Physiology, Ulm University, 89069 Ulm, Germany.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cyclic Nucleotide-Gated Cation Channels
Electrophysiology*
Humans
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Hypokalemic Periodic Paralysis / genetics
Hypokalemic Periodic Paralysis / metabolism*
Mutation
Potassium Channels / genetics
Potassium Channels / metabolism
Protons*
Sodium Channels / genetics
Sodium Channels / metabolism

Substances

Cyclic Nucleotide-Gated Cation Channels
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Potassium Channels
Protons
Sodium Channels