A decade after the Tokyo sarin attack: a review of neurological follow-up of the victims

Mil Med. 2007 Jun;172(6):607-10. doi: 10.7205/milmed.172.6.607.

Abstract

Objective: On March 20, 1995, sarin gas was used in Tokyo by members of the Japanese "Uhm-Shinrikiu" cult, killing 12 and injuring >5,500 innocent people. Most of the casualties were mildly injured. This article reviews the neurological follow-up data for some of the victims over the past decade.

Methods: We reviewed the published literature regarding neurological follow-up of the victims, dividing the data according to the time elapsed after the attack.

Results: The digit span test, finger-tapping test, and computerized posturography were the only performance tests that showed statistically significant differences between the victims and the control groups in some of the surveys. The main sequela 7 years after the attack was post-traumatic stress disorder.

Conclusions: The results emphasize the need for a national preparedness program for such mass casualty events, led by national health systems. This should include long-term, neurological, follow-up monitoring with performance tests and a post-traumatic stress disorder screening test.

MeSH terms

  • Brain Diseases / chemically induced
  • Brain Diseases / etiology*
  • Case-Control Studies
  • Chemical Terrorism*
  • Chemical Warfare Agents / toxicity*
  • Cognition Disorders / chemically induced
  • Cognition Disorders / etiology*
  • Emergency Service, Hospital / statistics & numerical data
  • Follow-Up Studies
  • Health Surveys
  • Humans
  • Japan
  • Sarin / toxicity*
  • Stress Disorders, Post-Traumatic / etiology*
  • Surveys and Questionnaires
  • Survivors
  • Time Factors
  • Transportation

Substances

  • Chemical Warfare Agents
  • Sarin