Abstract
Maintaining energy balance involves the dynamic control of appetite and energy expenditure. A new study from the Kadowaki laboratory (Kubota et al., 2007) shows that the adipocyte-derived hormone adiponectin increases appetite and reduces energy expenditure by stimulating AMPK in the hypothalamus.
MeSH terms
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AMP-Activated Protein Kinases
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Adiponectin / cerebrospinal fluid
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Adiponectin / genetics
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Adiponectin / physiology*
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Animals
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Eating
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Energy Metabolism
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Hypothalamus / enzymology*
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Hypothalamus / pathology
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Multienzyme Complexes / genetics
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Multienzyme Complexes / metabolism*
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Protein Serine-Threonine Kinases / genetics
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Protein Serine-Threonine Kinases / metabolism*
Substances
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Adiponectin
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Multienzyme Complexes
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Protein Serine-Threonine Kinases
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AMP-Activated Protein Kinases