Evaluation of real-time polymerase chain reaction for the detection of methicillin-resistant Staphylococcus aureus on environmental surfaces

Infect Control Hosp Epidemiol. 2007 Aug;28(8):1003-5. doi: 10.1086/519207. Epub 2007 Jun 11.

Abstract

We compared real-time polymerase chain reaction (RT-PCR) with in vitro culture for detecting methicillin-resistant Staphylococcus aureus in samples from environmental surfaces. The sensitivity of RT-PCR, compared with culture, was 92.5%, and the specificity was 51.4%. Because of poor specificity, the RT-PCR kit tested is not suitable for the detection of MRSA on hospital surfaces.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteriological Techniques / methods
  • Equipment and Supplies, Hospital / microbiology*
  • Fomites / microbiology*
  • Humans
  • Methicillin Resistance*
  • Polymerase Chain Reaction / methods
  • Polymerase Chain Reaction / standards*
  • Predictive Value of Tests
  • Staphylococcus aureus / classification*
  • Staphylococcus aureus / genetics
  • Staphylococcus aureus / isolation & purification