PI-PLCbeta-1 and activated Akt levels are linked to azacitidine responsiveness in high-risk myelodysplastic syndromes

Leukemia. 2008 Jan;22(1):198-200. doi: 10.1038/sj.leu.2404855. Epub 2007 Jul 12.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Azacitidine / therapeutic use*
  • Enzyme Inhibitors / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Myelodysplastic Syndromes / drug therapy*
  • Myelodysplastic Syndromes / metabolism*
  • Phosphatidylinositols / metabolism*
  • Phospholipase C beta / metabolism*
  • Proto-Oncogene Proteins c-akt / metabolism*

Substances

  • Enzyme Inhibitors
  • Phosphatidylinositols
  • Proto-Oncogene Proteins c-akt
  • PLCB1 protein, human
  • Phospholipase C beta
  • Azacitidine