Biochemistry. PI3K charges ahead

Science. 2007 Jul 13;317(5835):206-7. doi: 10.1126/science.1146073.
No abstract available

Publication types

  • Comment

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use
  • Catalytic Domain
  • Cell Membrane / enzymology
  • Cell Proliferation
  • Cell Survival
  • Dimerization
  • Enzyme Inhibitors / pharmacology
  • Enzyme Inhibitors / therapeutic use
  • Humans
  • Mutation
  • Neoplasms / drug therapy
  • Neoplasms / genetics*
  • Phosphatidylinositol 3-Kinases / chemistry
  • Phosphatidylinositol 3-Kinases / genetics*
  • Phosphatidylinositol 3-Kinases / metabolism*
  • Phosphoinositide-3 Kinase Inhibitors
  • Phosphorylation
  • Protein Structure, Tertiary
  • Protein Subunits
  • src Homology Domains

Substances

  • Antineoplastic Agents
  • Enzyme Inhibitors
  • Phosphoinositide-3 Kinase Inhibitors
  • Protein Subunits