HIPK2-induced p53Ser46 phosphorylation activates the KILLER/DR5-mediated caspase-8 extrinsic apoptotic pathway

Cell Death Differ. 2007 Oct;14(10):1837-9. doi: 10.1038/sj.cdd.4402186. Epub 2007 Jul 13.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apoptosis / physiology*
  • Carrier Proteins / metabolism*
  • Caspase 8 / metabolism*
  • Cell Line, Tumor
  • Female
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Phosphorylation
  • Protein Serine-Threonine Kinases / metabolism*
  • Receptors, TNF-Related Apoptosis-Inducing Ligand / metabolism*
  • Tumor Suppressor Protein p53 / metabolism*

Substances

  • Carrier Proteins
  • Receptors, TNF-Related Apoptosis-Inducing Ligand
  • Tumor Suppressor Protein p53
  • HIPK2 protein, human
  • Protein Serine-Threonine Kinases
  • Caspase 8