Symptoms of fatigue in chronic heart failure patients: clinical and psychological predictors

Eur J Heart Fail. 2007 Sep;9(9):922-7. doi: 10.1016/j.ejheart.2007.05.016. Epub 2007 Jul 12.

Abstract

Objective: To examine the role of clinical and psychological characteristics as predictors of fatigue in CHF.

Background: Little is known about predictors of fatigue in CHF. Next to heart failure characteristics, depressive symptoms and type-D personality may explain individual differences in fatigue.

Methods: At baseline, 136 CHF outpatients (age<or=80 years) completed a questionnaire to assess depressive symptoms, type-D personality and cardiac symptoms. At one-year follow-up, they completed the Dutch Exertion Fatigue Scale and the Fatigue Assessment Scale to assess symptoms of fatigue. Medical information was obtained from the patients' medical records.

Results: Exertion fatigue and general fatigue were identified as different manifestations of fatigue. We found that exertion fatigue at 12-month follow-up was predicted by decreased exercise capacity (beta=-.35; p<.001), dyspnoea (beta=24; p=.002), hypertension (beta=.16; p=.03), and depressive symptoms (beta=.16; p=.05). In contrast, general fatigue at 12-month follow-up was predicted by dyspnoea (beta=.24; p=.003), depressive symptoms (beta=.27; p<.001), type-D personality (beta=17; p=.03), and sleep problems (beta=.20; p=.01). Together, these variables explained 32% and 37% of the variance, respectively.

Conclusion: The present study showed that fatigue was related to both clinical and psychological characteristics. The use of this knowledge may lead to a better understanding and treatment of the clinical manifestations of fatigue in CHF.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Chronic Disease
  • Depressive Disorder / diagnosis
  • Depressive Disorder / psychology
  • Fatigue / etiology*
  • Fatigue / psychology
  • Female
  • Heart Failure / complications*
  • Heart Failure / psychology
  • Humans
  • Male
  • Middle Aged
  • Personality Tests
  • Prospective Studies