Abstract
Publications reporting results of small-molecule screens are becoming more common as academic researchers increasingly make use of high-throughput screening (HTS) facilities. However, no standards have been formally established for reporting small-molecule screening data, and often key information important for the evaluation and interpretation of results is omitted in published HTS protocols. Here, we propose concise guidelines for reporting small-molecule HTS data.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, N.I.H., Intramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Chemistry, Pharmaceutical / methods*
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Combinatorial Chemistry Techniques*
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Dose-Response Relationship, Drug
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Drug Design
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Drug Evaluation, Preclinical
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Guidelines as Topic
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Humans
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Inhibitory Concentration 50
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Models, Chemical
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Molecular Conformation
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Pharmaceutical Preparations
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Technology, Pharmaceutical / methods*
Substances
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Pharmaceutical Preparations