Gordonia species: emerging pathogens in pediatric patients that are identified by 16S ribosomal RNA gene sequencing

Anne J Blaschke; Jeffrey Bender; Carrie L Byington; Kent Korgenski; Judy Daly; Cathy A Petti; Andrew T Pavia; Krow Ampofo

doi:10.1086/520018

Gordonia species: emerging pathogens in pediatric patients that are identified by 16S ribosomal RNA gene sequencing

Clin Infect Dis. 2007 Aug 15;45(4):483-6. doi: 10.1086/520018. Epub 2007 Jul 5.

Authors

Anne J Blaschke¹, Jeffrey Bender, Carrie L Byington, Kent Korgenski, Judy Daly, Cathy A Petti, Andrew T Pavia, Krow Ampofo

Affiliation

¹ Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Utah, Salt Lake City, UT, USA. [email protected]

PMID: 17638199
DOI: 10.1086/520018

Abstract

Gordonia species are emerging pathogens that are often misidentified as Rhodococcus or Nocardia species but are reliably distinguished by 16S ribosomal RNA gene sequencing. We present a case series of 6 episodes of catheter-associated infection caused by Gordonia species in 5 patients seen at a tertiary care pediatric hospital and describe the management and outcomes of this infection in adults and children.

MeSH terms

Actinomycetales Infections / diagnosis*
Actinomycetales Infections / drug therapy
Actinomycetales Infections / microbiology
Anti-Bacterial Agents / therapeutic use
Catheters, Indwelling / microbiology
Child
Child, Preschool
Drug Therapy, Combination
Gordonia Bacterium / genetics
Gordonia Bacterium / isolation & purification*
Humans
Infant
RNA, Ribosomal, 16S / genetics*
Sequence Analysis, DNA

Substances

Anti-Bacterial Agents
RNA, Ribosomal, 16S