Application of single-photon emission computed tomography (SPECT) with 99mTc-MAA in evaluation of perfusion patterns during hepatic infusion chemotherapy

Ann Nucl Med. 1991 Sep;5(3):123-6. doi: 10.1007/BF03164625.

Abstract

In 6 patients receiving hepatic artery infusion chemotherapy for liver metastases, planar and single-photon emission computed tomography (SPECT) images of the abdomen were obtained after intravenous injection of 99mTc-phytate, and intra-catheter injection of 99mTc-MAA in the same geometrical settings. With this method, the three-dimensional intra- and extra-hepatic distribution of the agents during hepatic artery infusion chemotherapy can be evaluated.

MeSH terms

  • Aged
  • Antineoplastic Agents / administration & dosage*
  • Antineoplastic Agents / pharmacokinetics
  • Antineoplastic Agents / therapeutic use
  • Carcinoid Tumor / diagnostic imaging
  • Carcinoid Tumor / drug therapy
  • Carcinoid Tumor / secondary
  • Colonic Neoplasms / diagnostic imaging
  • Colonic Neoplasms / drug therapy
  • Female
  • Hepatic Artery
  • Humans
  • Infusions, Intra-Arterial
  • Leiomyosarcoma / diagnostic imaging
  • Leiomyosarcoma / drug therapy
  • Leiomyosarcoma / secondary
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / secondary*
  • Male
  • Middle Aged
  • Rectal Neoplasms / diagnostic imaging
  • Rectal Neoplasms / drug therapy
  • Technetium Tc 99m Aggregated Albumin*
  • Tomography, Emission-Computed, Single-Photon*

Substances

  • Antineoplastic Agents
  • Technetium Tc 99m Aggregated Albumin