Palliation in patients with malignant gastric outlet obstruction with a newly designed enteral stent: a multicenter study

Gastrointest Endosc. 2007 Aug;66(2):355-60. doi: 10.1016/j.gie.2006.11.060.

Abstract

Background: Through-the-scope (TTS) stents facilitate palliative enteral stent placement. However, most TTS stents are braided, a characteristic that has been associated with significant foreshortening and relatively frequent migration.

Objectives: To evaluate clinical experience with a new woven enteral stent in the treatment of gastric outlet obstruction.

Design: From January 2005 to August 2006, patients with unresectable malignant gastric outlet obstruction were offered stent placement with a new woven stent.

Setting: Three referral hospitals in Japan.

Patients: Thirty-seven consecutive patients with malignant gastric outlet obstruction.

Interventions: A newly designed enteral stent was placed by using the TTS placement technique.

Main outcome measurements: Palliation efficacy and safety of the new stents.

Results: Stent placement was successful in 36 of 37 patients (technical success, 97%). Thirty-four patients were able to tolerate oral intake without obstructive symptoms (clinical success, 94.4%). Complications occurred in 16.2% of patients, comprising 2 cases of primary stent dysfunction, 1 perforation, 1 GI bleeding, 1 stent obstruction, and 1 biliary stent dysfunction. No migration was seen during the median follow-up period of 68 days.

Limitations: Small sample size and relatively brief follow-up.

Conclusions: A newly developed enteral stent with higher flexibility and less foreshortening offers comparable clinical outcome to existing stents and a lower frequency of complications, including migration.

Publication types

  • Multicenter Study

MeSH terms

  • Aged
  • Alloys
  • Equipment Design
  • Female
  • Gastric Outlet Obstruction / etiology
  • Gastric Outlet Obstruction / therapy*
  • Humans
  • Male
  • Middle Aged
  • Palliative Care*
  • Pancreatic Neoplasms / complications
  • Pancreatic Neoplasms / mortality
  • Stents* / adverse effects
  • Stomach Neoplasms / complications
  • Stomach Neoplasms / mortality
  • Survival Rate

Substances

  • Alloys
  • nitinol