Regression of choroidal metastasis from breast carcinoma following Letrozole therapy

Clin Exp Ophthalmol. 2007 Jul;35(5):492-4. doi: 10.1111/j.1442-9071.2007.01520.x.

Abstract

Metastasis to the choroid from primary tumours elsewhere in the body is not an infrequent occurrence. Management of such metastasis may involve modalities such as radiotherapy, chemotherapy, photocoagulation and surgical resection. The role of hormonal therapy is poorly defined in the management of these tumours. Herein regression of choroidal metastasis from primary breast carcinoma following antihormonal therapy with the antioestrogen drug Letrozole is reported.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Agents / therapeutic use*
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / pathology
  • Choroid Neoplasms / drug therapy*
  • Choroid Neoplasms / secondary
  • Estrogen Receptor Modulators / therapeutic use*
  • Female
  • Fluorescein Angiography
  • Humans
  • Letrozole
  • Nitriles / therapeutic use*
  • Remission Induction
  • Tomography, Optical Coherence
  • Triazoles / therapeutic use*

Substances

  • Antineoplastic Agents
  • Estrogen Receptor Modulators
  • Nitriles
  • Triazoles
  • Letrozole