Antimicrobial and antiviral activity of xylosyl-methylthio-adenosine, a naturally occurring analogue of methylthio-adenosine from Doris verrucosa

Experientia. 1991 Dec 1;47(11-12):1228-9. doi: 10.1007/BF01918391.

Abstract

Xylosyl-methylthio-adenosine, a naturally occurring analogue of 5'-deoxy-5'-methylthio-adenosine, has been postulated to play a protective role during egg development in the mollusc Doris verrucosa. However, in vitro tests showed that this analogue is devoid of activity against fungi, bacteria and viruses.

MeSH terms

  • Adenosine / analogs & derivatives*
  • Adenosine / pharmacology
  • Animals
  • Anti-Bacterial Agents*
  • Antifungal Agents*
  • Antiviral Agents* / pharmacology
  • Cell Survival / drug effects
  • Cells, Cultured
  • Deoxyadenosines / pharmacology*
  • Mollusca / chemistry*
  • Thionucleosides / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Antiviral Agents
  • Deoxyadenosines
  • Thionucleosides
  • 9-xylosyladenine
  • 9-(5'-deoxy-5'-(methylthio)-xylofuranosyl)adenine
  • 5'-methylthioadenosine
  • Adenosine