What factors influence the results of coronary artery bypass grafting in aged patients?

J Cardiovasc Surg (Torino). 2007 Aug;48(4):505-8.

Abstract

Aim: Early and late results were studied in order to improve the indication for coronary artery bypass grafting (CABG) and to enhance

Methods: A total of 1 973 patients aged 70 years and older who had undergone isolated CABG were studied. Elective operations (EL) were performed in 1 716 patients and 257 patients underwent urgent or emergency operations (UR/EM). Patients were divided into two groups; 104 patients aged 80 years and older (Oct. Group) and 1 869 patients of septuagenarians (Sept. Group). There were no differences between the groups in the number of diseased vessels.

Results: Total operative mortality rates in the Oct. and the Sept. groups were 7% and 4%, respectively. The operative mortality of elective surgery was 4% in both groups. The operative mortality of UR/EM CABG was significantly higher in the Oct. group than in the Sept. group (21% vs 6%). Operative mortality was significantly higher in patients with preoperative poor (<49%) left ventricular ejection fraction (LVEF) than in patients with higher (>50%) LVEF (6% vs 3%). Among preoperative risk factors, diabetes mellitus and peripheral vascular disease were significant contributory factors to operative death. In the follow-up study, 70% patients of the Oct. group and 72% patients of the Sept. group survived. Preoperative number of diseased vessels and number of CABG grafts did not influence the early and late

Conclusion: Preoperative poor LVEF, diabetes mellitus and peripheral vascular disease were significant contributory factors to operative death. When feasible, CABG in octogenarians should be performed electively.

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Coronary Artery Bypass / adverse effects*
  • Coronary Artery Bypass / mortality*
  • Coronary Artery Disease / complications
  • Coronary Artery Disease / mortality*
  • Coronary Artery Disease / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Patient Selection
  • Reoperation
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index
  • Stroke Volume
  • Treatment Outcome