Abstract
Acute myeloid leukemia (AML)'s diagnosis is clinical and biological. We report here 80 AML with cytology and immunophenotype features to establish correlations. 21 AML1, 23 AML2, 12 AML3, 2 AML4, 18 AML5 and 3 AML6 were diagnosed by cytology. Only one case of AML0 was diagnosed by immunophenotype. Myelogysplasia is present in 29.8% cases. CD19 and CD56 expression was significantly associated to AML +t(8;21). Additionally, concomitant negativity of CD34 and HLA-DR was discrimininatif to AML3 diagnosis. Prognostic value to expression some CD needs time backwards.
MeSH terms
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Adolescent
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Adult
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Antigens, CD19 / analysis
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Antigens, CD34 / analysis
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B-Lymphocytes / pathology
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CD56 Antigen / analysis
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Child
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Child, Preschool
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Female
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HLA-DR Antigens / analysis
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Humans
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Immunohistochemistry
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Immunophenotyping
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Leukemia, Myeloid, Acute / classification
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Leukemia, Myeloid, Acute / immunology
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Leukemia, Myeloid, Acute / pathology*
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Male
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Middle Aged
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Myelodysplastic Syndromes / immunology
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Myelodysplastic Syndromes / pathology
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Myeloid Cells / pathology
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Peroxidase / analysis
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Prognosis
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T-Lymphocytes / pathology
Substances
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Antigens, CD19
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Antigens, CD34
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CD56 Antigen
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HLA-DR Antigens
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Peroxidase