Abstract
We describe seven patients with genetically confirmed Huntington's disease (HD) who had non-choreic movement disorders as presenting symptoms or signs. Patients with movement disorders other than chorea in the early stages tended to have larger CAG trinucleotide repeat expansion in comparison with more "typical" HD patients.
MeSH terms
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Adult
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Dystonia / diagnosis
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Dystonia / genetics
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Electrophoresis, Polyacrylamide Gel
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Female
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Humans
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Huntington Disease / diagnosis
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Huntington Disease / genetics*
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Parkinsonian Disorders / diagnosis
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Parkinsonian Disorders / genetics
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Polymerase Chain Reaction
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Tics / diagnosis
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Tics / genetics
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Tomography, X-Ray Computed
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Trinucleotide Repeat Expansion / genetics*