Prevalence of dementia in intellectual disability using different diagnostic criteria

Br J Psychiatry. 2007 Aug:191:150-7. doi: 10.1192/bjp.bp.106.028845.

Abstract

Background: Diagnosis of dementia is complex in adults with intellectual disability owing to their pre-existing deficits and different presentation.

Aims: To describe the clinical features and prevalence of dementia and its subtypes, and to compare the concurrent validity of dementia criteria in older adults with intellectual disability.

Method: The Becoming Older with Learning Disability (BOLD) memory study is a two-stage epidemiological survey of adults with intellectual disability without Down syndrome aged 60 years and older, with comprehensive assessment of people who screen positive. Dementia was diagnosed according to ICD-10, DSM-IV and DC-LD criteria.

Results: The DSM-IV dementia criteria were more inclusive. Diagnosis using ICD-10 excluded people with even moderate dementia. Clinical subtypes of dementia can be recognised in adults with intellectual disability. Alzheimer's dementia was the most common, with a prevalence of 8.6% (95% CI 5.2-13.0), almost three times greater than expected.

Conclusions: Dementia is common in older adults with intellectual disability, but prevalence differs according to the diagnostic criteria used. This has implications for clinical practice.

Publication types

  • Comparative Study
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Dementia / diagnosis
  • Dementia / epidemiology*
  • Dementia / psychology
  • Female
  • Humans
  • Intellectual Disability / psychology*
  • Learning Disabilities / psychology*
  • London / epidemiology
  • Male
  • Middle Aged
  • Prevalence
  • Psychiatric Status Rating Scales / statistics & numerical data