Abstract
The first two articles in this series discussed the fundamental concept of T-cell co-stimulation as a key event in the induction of any immune response, in addition to reviewing the current data on the role of co-stimulatory molecules for the induction and progression of allergic airway diseases. Based on these considerations, this final edition will delineate and discuss novel strategies for the prevention and/or therapy of allergic diseases based upon the modulation of co-stimulation.
MeSH terms
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Animals
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Antibodies, Monoclonal / pharmacology*
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Antigens, CD / immunology*
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Antigens, Differentiation, T-Lymphocyte / immunology
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Asthma / immunology*
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Asthma / therapy*
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Bronchial Hyperreactivity
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Cytokines / immunology*
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Humans
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Inducible T-Cell Co-Stimulator Protein
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Inflammation
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Ligands
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Lymphocyte Activation
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Mice
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Mice, Inbred Strains
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Mice, Knockout
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Models, Animal
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Models, Biological
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T-Lymphocytes / immunology*
Substances
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Antibodies, Monoclonal
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Antigens, CD
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Antigens, Differentiation, T-Lymphocyte
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Cytokines
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ICOS protein, human
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Icos protein, mouse
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Inducible T-Cell Co-Stimulator Protein
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Ligands