Efficacy of autovaccination therapy on post-coronary artery bypass grafting methicillin-resistant Staphylococcus aureus mediastinitis

Interact Cardiovasc Thorac Surg. 2007 Apr;6(2):228-9. doi: 10.1510/icvts.2006.137901. Epub 2007 Jan 5.

Authors

Caterina Rizzo¹, Gianluca Brancaccio, Danila De Vito, Giovanni Rizzo

Affiliation

¹ Department of Pharmaco-Biology, University of Bari, Italy.

PMID: 17669818
DOI: 10.1510/icvts.2006.137901

Abstract

We report a case of mediastinitis successfully treated with autovaccine therapy, once conventional surgical and medical therapies had failed.

Publication types

Case Reports

MeSH terms

Aged
Anti-Bacterial Agents / therapeutic use
Anti-Infective Agents, Local / therapeutic use
Coronary Artery Bypass*
Coronary Stenosis / surgery*
Debridement
Gentamicins / therapeutic use
Humans
Male
Mediastinitis / drug therapy
Mediastinitis / microbiology
Mediastinitis / surgery
Mediastinitis / therapy*
Methicillin Resistance*
Povidone-Iodine / therapeutic use
Staphylococcal Infections / drug therapy
Staphylococcal Infections / microbiology
Staphylococcal Infections / surgery
Staphylococcal Infections / therapy*
Staphylococcal Vaccines / therapeutic use*
Staphylococcus aureus / immunology*
Staphylococcus aureus / isolation & purification
Surgical Wound Infection / drug therapy
Surgical Wound Infection / microbiology
Surgical Wound Infection / surgery
Surgical Wound Infection / therapy*
Teicoplanin / therapeutic use
Therapeutic Irrigation
Treatment Failure
Treatment Outcome
Vancomycin / therapeutic use

Substances

Anti-Bacterial Agents
Anti-Infective Agents, Local
Gentamicins
Staphylococcal Vaccines
Teicoplanin
Vancomycin
Povidone-Iodine