Stereoselective synthesis of (E)- and (Z)-enol ethers from beta-amino aldehydes

Arch Pharm Res. 2007 Jun;30(6):695-700. doi: 10.1007/BF02977630.

Abstract

Stereocontrolled methods for the direct and divergent synthesis of the silylenol ethers possessing amino group from beta-amino aldehydes have been achieved. These enol ethers with the defined olefin geometry could be key building blocks for the synthesis of the medicinally impor tant compounds.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry*
  • Alkenes / chemistry
  • Alkylation
  • Benzyl Compounds / chemical synthesis
  • Ethers / chemical synthesis*
  • Indicators and Reagents
  • Magnetic Resonance Spectroscopy
  • Methylation
  • Silanes / chemical synthesis
  • Stereoisomerism

Substances

  • Aldehydes
  • Alkenes
  • Benzyl Compounds
  • Ethers
  • Indicators and Reagents
  • Silanes