Joint independent component analysis for simultaneous EEG-fMRI: principle and simulation

Int J Psychophysiol. 2008 Mar;67(3):212-21. doi: 10.1016/j.ijpsycho.2007.05.016. Epub 2007 Jul 12.

Abstract

An optimized scheme for the fusion of electroencephalography and event related potentials with functional magnetic resonance imaging (BOLD-fMRI) data should simultaneously assess all available electrophysiologic and hemodynamic information in a common data space. In doing so, it should be possible to identify features of latent neural sources whose trial-to-trial dynamics are jointly reflected in both modalities. We present a joint independent component analysis (jICA) model for analysis of simultaneous single trial EEG-fMRI measurements from multiple subjects. We outline the general idea underlying the jICA approach and present results from simulated data under realistic noise conditions. Our results indicate that this approach is a feasible and physiologically plausible data-driven way to achieve spatiotemporal mapping of event related responses in the human brain.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Algorithms
  • Brain Mapping / instrumentation
  • Brain Mapping / methods*
  • Cerebral Cortex / blood supply
  • Cerebral Cortex / metabolism
  • Cerebrovascular Circulation
  • Computer Simulation*
  • Electroencephalography / instrumentation*
  • Humans
  • Magnetic Resonance Imaging / instrumentation*
  • Oxygen / metabolism
  • Principal Component Analysis*
  • Reproducibility of Results
  • Signal Processing, Computer-Assisted*

Substances

  • Oxygen