Successful outcome of human metapneumovirus (hMPV) pneumonia in a lung transplant recipient treated with intravenous ribavirin

J Heart Lung Transplant. 2007 Aug;26(8):862-4. doi: 10.1016/j.healun.2007.05.020. Epub 2007 Jul 12.

Abstract

Human metapneumovirus (hMPV) has recently been shown to be a prominent cause of respiratory infections in immunocompromised hosts, and is associated with high morbidity and mortality. We report a case of hMPV pneumonia in a lung transplant recipient presenting with respiratory failure and sepsis syndrome. hMPV was diagnosed by polymerase chain reaction, and treated with intravenous ribavirin with a successful outcome.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / administration & dosage*
  • Biopsy
  • Bronchoscopy
  • DNA, Viral / analysis
  • Diagnosis, Differential
  • Female
  • Follow-Up Studies
  • Humans
  • Lung / pathology
  • Lung / virology
  • Lung Transplantation*
  • Metapneumovirus / genetics
  • Metapneumovirus / isolation & purification*
  • Middle Aged
  • Paramyxoviridae Infections / diagnosis
  • Paramyxoviridae Infections / drug therapy*
  • Paramyxoviridae Infections / virology
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / drug therapy*
  • Pneumonia, Viral / virology
  • Postoperative Complications
  • Pulmonary Disease, Chronic Obstructive / surgery
  • Ribavirin / administration & dosage*

Substances

  • Antiviral Agents
  • DNA, Viral
  • Ribavirin