Bioconjugation of biotinylated PAMAM dendrons to avidin

Chem Commun (Camb). 2007 Sep 7:(33):3441-3. doi: 10.1039/b709080c. Epub 2007 Jul 24.

Abstract

The biotin-terminated PAMAM dendron has been synthesized and the asymmetric dendron used to modify the protein avidin via non-covalent bioconjugation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Avidin / chemistry*
  • Binding, Competitive
  • Biotin / chemistry*
  • Biotinylation
  • Dendrimers
  • Drug Carriers / chemical synthesis
  • Drug Carriers / chemistry*
  • Models, Molecular
  • Polyamines / chemical synthesis
  • Polyamines / chemistry*
  • Protein Binding

Substances

  • Dendrimers
  • Drug Carriers
  • PAMAM Starburst
  • Polyamines
  • Avidin
  • Biotin