Abstract
This report describes an outbreak of Legionnaires' disease in severely immunosuppressed patients hospitalised at a cancer centre. Universal urine antigen testing and early levofloxacin therapy appeared to lower case fatality rates in comparison with previous reports concerning this high-risk population. This diagnostic and therapeutic strategy should be considered when facing a nosocomial outbreak of Legionnaires' disease in immunosuppressed hosts.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Antigens, Bacterial / urine
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Cancer Care Facilities
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Cross Infection / drug therapy*
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Cross Infection / epidemiology
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Cross Infection / immunology*
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Cross Infection / microbiology
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Female
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Humans
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Immunocompromised Host*
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Legionnaires' Disease / drug therapy*
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Legionnaires' Disease / epidemiology
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Legionnaires' Disease / immunology*
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Levofloxacin*
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Male
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Middle Aged
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Ofloxacin / therapeutic use*
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Spain / epidemiology
Substances
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Antigens, Bacterial
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Levofloxacin
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Ofloxacin