Abstract
The meroditerpenoids atomaric acid (1), epitaondiol (2) and the peroxylactone of 5'a-desmethyl-5'-acetylatomaric acid (3) were isolated from the Brazilian brown alga Stypopodium zonale collected in two localities (Búzios and Marataízes, RJ and ES States). These compounds showed strong anti-HSV-1 activity in vitro but neither of them inhibited the transcriptase reverse enzyme of HIV-1.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antiviral Agents / administration & dosage
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Antiviral Agents / pharmacology*
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Antiviral Agents / therapeutic use
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Brazil
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Diterpenes / administration & dosage
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Diterpenes / pharmacology
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Diterpenes / therapeutic use
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HIV-1 / drug effects*
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Herpesvirus 1, Human / drug effects*
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Humans
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Medicine, Traditional
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Microbial Sensitivity Tests
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Phytotherapy*
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
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Seaweed*
Substances
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Antiviral Agents
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Diterpenes
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Plant Extracts