Established treatments of skin hypermelanoses

J Cosmet Dermatol. 2006 Dec;5(4):303-8. doi: 10.1111/j.1473-2165.2006.00276.x.

Abstract

Cutaneous hypermelanoses are frequently encountered conditions that can have severe adverse psychosocial and emotional effects on affected patients. Melasma, postinflammatory hyperpigmentation, drug-induced pigmentation, and erythema dischromicum perstans are among the most common cutaneous disorders leading to acquired skin hyperpigmentation. The treatment of these disorders is often challenging and requires a great deal of patience from the patient and a wealth of experience and knowledge from the dermatologist. Current treatments include depigmenting agents, chemical peels, and lasers. The ideal bleaching agent has to fulfill certain pharmacologic criteria. It should have a potent bleaching effect with a rapid time of onset, carry no side effects, and lead to a permanent removal of undesired pigment. We review the established treatment approaches of cutaneous hyperpigmentation based on literature review and our personal experience.

Publication types

  • Review

MeSH terms

  • Dermatologic Agents
  • Humans
  • Hyperpigmentation / etiology
  • Hyperpigmentation / therapy*
  • Laser Therapy

Substances

  • Dermatologic Agents