Separation of nanoparticles by gel electrophoresis according to size and shape

Nano Lett. 2007 Sep;7(9):2881-5. doi: 10.1021/nl071615y. Epub 2007 Aug 24.

Abstract

We demonstrate the separation of gold and silver nanoparticles according to their size and shape by agarose gel electrophoresis after coating them with a charged polymer layer. The separation is monitored optically using the size- and shape-dependent plasmon resonance of noble metal particles and confirmed by transmission electron microscopy (TEM). Electrophoretic mobilities are quantitatively explained by a model based on the Henry formula, providing a theoretical framework for predicting gel mobilities of polymer coated nanoparticles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Comet Assay / methods*
  • Computer Simulation
  • Gold / chemistry*
  • Gold / isolation & purification*
  • Models, Chemical*
  • Nanostructures / chemistry*
  • Nanotechnology / methods
  • Particle Size
  • Silver / chemistry*
  • Silver / isolation & purification*

Substances

  • Silver
  • Gold