Abstract
Gallbladder wall thickening measured by ultrasound was significantly associated with severe dengue, as well as with hallmark features of thrombocytopenia and elevated hematocrit/hemoconcentration, in children with suspected dengue in Nicaragua. We demonstrate that gallbladder wall thickening serves as a clinically relevant diagnostic test and prognostic indicator of severe dengue in pediatric populations.
Publication types
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Research Support, N.I.H., Extramural
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Validation Study
MeSH terms
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Adolescent
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Antibodies / blood
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Child
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Child, Preschool
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Dengue / diagnosis
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Dengue / diagnostic imaging*
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Dengue Virus / immunology
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Dengue Virus / isolation & purification
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Female
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Gallbladder / diagnostic imaging*
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Gallbladder / pathology
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Hospitals, Pediatric
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Humans
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Immunoglobulin M / blood
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Male
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Nicaragua
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Prognosis
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Ultrasonography
Substances
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Antibodies
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Immunoglobulin M