Visual impairment and retinopathy in people with normal glucose tolerance, impaired glucose tolerance, and newly diagnosed NIDDM

Diabetes Care. 1991 Oct;14(10):914-8. doi: 10.2337/diacare.14.10.914.

Abstract

Objective: Prevalence rates of visual impairment and retinopathy were compared in 1992 people with normal glucose tolerance, impaired glucose tolerance (IGT), or newly diagnosed non-insulin-dependent diabetes mellitus (NIDDM).

Research design and methods: Glucose tolerance status was based on an oral glucose tolerance test after exclusion of those with a history of diabetes and/or diabetes medication use in an upper middle-class community of older white adults in southern California between 1984 and 1987.

Results: Although many sex-specific comparisons were made between glucose tolerance groups, only a few emerged as statistically significant. Among those, women with IGT had significantly higher age-adjusted rates of visual impairment (10.8%) than women with normal glucose tolerance (4.4%). Among men, those with IGT had significantly higher age-adjusted rates of visual impairment (7.9%) than men with newly diagnosed NIDDM (4.0%).

Conclusions: Low frequencies of retinopathy were found in all three glucose tolerance groups.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Age Factors
  • Aged
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / metabolism
  • Diabetic Retinopathy / metabolism*
  • Female
  • Glucose / metabolism
  • Glucose Tolerance Test*
  • Humans
  • Male
  • Middle Aged
  • Sex Factors
  • Vision Disorders / etiology*
  • Vision Disorders / metabolism

Substances

  • Glucose