Gadolinium-DTPA enhanced gradient echo magnetic resonance scans in first episode of psychosis and chronic schizophrenic patients

Psychiatry Res. 1991 Nov;40(3):203-7. doi: 10.1016/0925-4927(91)90011-e.

Abstract

Ten male schizophrenic patients underwent Gadolinium-DTPA (Gd-DTPA) enhanced magnetic resonance (MR) imaging to determine the utility of paramagnetic contrast agents in evaluating neuropathology. MR images enhanced by Gd-DTPA demonstrated no defect in the integrity of the blood-brain barrier.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Blood-Brain Barrier / physiology*
  • Cerebral Cortex / pathology
  • Cerebral Ventricles / pathology
  • Chronic Disease
  • Contrast Media*
  • Gadolinium DTPA
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Organometallic Compounds*
  • Pentetic Acid*
  • Schizophrenia / pathology*
  • Schizophrenic Psychology*

Substances

  • Contrast Media
  • Organometallic Compounds
  • Pentetic Acid
  • Gadolinium DTPA