[Treatment guidelines for non-schizophrenic psychotic disorders?]

Psychiatr Prax. 2007 Nov;34(8):370-6. doi: 10.1055/s-2007-970964. Epub 2007 Sep 5.
[Article in German]

Abstract

Objective: To provide an overview of diagnostics, outcome and treatment of "non-schizophrenic psychotic disorders" (ICD-10: delusional disorders, acute and transient psychotic disorders and schizoaffective disorders).

Methods: Literature was identified by searches in "Medline" and "Cochrane Database of Systematic Reviews".

Results: The frequency of "non-schizophrenic psychotic disorders" within the whole diagnostic group "schizophrenia, schizotypal and delusional disorders" (ICD-10) ranges between 22% and 49%. Patients with these disorders show a more favourable long-term outcome than those with schizophrenia. With regard to therapy, as yet only a small empirical database exists. The comparability of those studies is limited by the use of different diagnostic criteria. There are only few evidence-based treatment guidelines for these disorders.

Conclusions: There is a substantial need for controlled studies on the treatment of "non-psychotic schizophrenic disorders". Alternatively, clinical guidelines could be based on a dichotomy of affective and schizophrenic disorders or on a dimensional approach.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Antipsychotic Agents / therapeutic use*
  • Controlled Clinical Trials as Topic
  • Diagnostic and Statistical Manual of Mental Disorders
  • Evidence-Based Medicine*
  • Humans
  • International Classification of Diseases
  • Lithium Compounds / therapeutic use
  • Practice Guidelines as Topic*
  • Prognosis
  • Psychotic Disorders / classification
  • Psychotic Disorders / diagnosis
  • Psychotic Disorders / drug therapy*
  • Schizophrenia / classification
  • Schizophrenia / diagnosis
  • Schizophrenia / drug therapy
  • Secondary Prevention

Substances

  • Antipsychotic Agents
  • Lithium Compounds