A new family of histamine H3 receptor antagonists based on a natural product: discovery, SAR, and properties of the series

Inflamm Res. 2007 Apr:56 Suppl 1:S47-8. doi: 10.1007/s00011-006-0523-9.
No abstract available

MeSH terms

  • Alkaloids* / chemistry
  • Alkaloids* / metabolism
  • Animals
  • Dose-Response Relationship, Drug
  • Drug Design
  • Guanosine Triphosphate / metabolism
  • Histamine Agonists / metabolism
  • Histamine Antagonists* / chemistry
  • Histamine Antagonists* / metabolism
  • Humans
  • Male
  • Molecular Structure
  • Rats
  • Receptors, Histamine H3 / metabolism*
  • Structure-Activity Relationship

Substances

  • Alkaloids
  • Histamine Agonists
  • Histamine Antagonists
  • Receptors, Histamine H3
  • Guanosine Triphosphate
  • conessine