Intraoperative ultrasound to define focal cortical dysplasia in epilepsy surgery

Epilepsia. 2008 Jan;49(1):156-8. doi: 10.1111/j.1528-1167.2007.01268.x. Epub 2007 Sep 6.

Abstract

Focal cortical dyplasia (FCD) is a frequent cause of medication-resistant focal epilepsy. Patients with FCD may benefit from epilepsy surgery. However, it is difficult to intraoperatively define lesion boundaries. In this case report we present a novel tool to identify FCD intraoperatively. A patient with frontal lobe epilepsy underwent resection of a left frontomesial FCD. Image guidance was achieved by intraoperative ultrasound, which depicted the lesion with a higher resolution than preoperative MRI. Postoperatively the patient remained seizure free. Intraoperative ultrasound may be helpful in identifying and targeting subtle epileptogenic lesions, which are difficult to visualize.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Corpus Callosum / pathology
  • Disease-Free Survival
  • Electroencephalography
  • Epilepsies, Partial / diagnosis
  • Epilepsies, Partial / pathology
  • Epilepsies, Partial / surgery*
  • Epilepsy, Frontal Lobe / diagnosis
  • Epilepsy, Frontal Lobe / pathology
  • Epilepsy, Frontal Lobe / surgery
  • Frontal Lobe / abnormalities*
  • Frontal Lobe / pathology
  • Frontal Lobe / surgery
  • Gyrus Cinguli / pathology
  • Humans
  • Magnetic Resonance Imaging / statistics & numerical data
  • Male
  • Malformations of Cortical Development / pathology
  • Malformations of Cortical Development / surgery*
  • Monitoring, Intraoperative / methods*
  • Monitoring, Intraoperative / statistics & numerical data
  • Preoperative Care / statistics & numerical data
  • Treatment Outcome
  • Ultrasonography / methods*