Successful treatment of extended epidural abscess and long segment osteomyelitis: a case report and review of the literature

Surg Neurol. 2008 Feb;69(2):117-20; discussion 120. doi: 10.1016/j.surneu.2006.12.047. Epub 2007 Sep 6.

Abstract

Background: Spinal osteomyelitis and epidural abscess are complicated medical conditions. Diagnosis is often delayed because of cormorbidity. The time of instrumentation is still controversial. However, there is no doubting the indication of spinal hardware implantation when spinal fusion is needed. Long segment osteomyelitis and extended epidural abscess are rare. The treatment is challenging for neurosurgeons. We report a case of extended epidural abscesses and long segments of osteomyelitis.

Methods: One-stage meticulous debridement, anterior cervical corpectomies, and spinal fusion with mesh cage and titanium plate were performed on the patient. Hyperbaric oxygenation and 6 weeks of intravenous antibiotics were prescribed as adjuvant therapy.

Results: Both clinical presentations and imaging studies showed a good response to the treatment. The patient returned to his life 3 months later.

Conclusions: This case illustrates that spinal instrumentation is not an absolute contraindication in the presence of epidural abscesses and vertebral osteomyelitis. Combined surgical debridement at a critical level, with adjuvant antibiotics and hyperbaric oxygenation, is a safe and effective therapy in those with neurologic deficits, spinal instability, and extended epidural abscess.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Cervical Vertebrae*
  • Epidural Abscess / diagnosis
  • Epidural Abscess / microbiology
  • Epidural Abscess / therapy*
  • Humans
  • Hyperbaric Oxygenation
  • Male
  • Middle Aged
  • Osteomyelitis / diagnosis
  • Osteomyelitis / microbiology
  • Osteomyelitis / therapy*
  • Oxacillin / administration & dosage
  • Spinal Fusion / methods*
  • Staphylococcal Infections / complications
  • Staphylococcal Infections / diagnosis
  • Staphylococcal Infections / therapy*

Substances

  • Anti-Bacterial Agents
  • Oxacillin