Daphnogirins A and B, two biflavones from Daphne giraldii

Chem Pharm Bull (Tokyo). 2007 Sep;55(9):1287-90. doi: 10.1248/cpb.55.1287.

Abstract

Two new biflavonoids, daphnogirins A (1) and B (2), were obtained from the roots of Daphne giraldii. Their structures were established on the basis of the spectral data and X-ray diffraction data of the co-crystal of 1 and 2. Daphnogrins A and B have the same configuration at C-1 and opposite configurations at C-16 and C-17. Oxygen radical scavenging assay has indicated that they are of significant antioxidative activity.

MeSH terms

  • Antioxidants / chemistry
  • Chromans / chemistry
  • Crystallography, X-Ray
  • Daphne / chemistry*
  • Flavones / chemistry*
  • Fluorescein / chemistry
  • Free Radical Scavengers / chemistry
  • Magnetic Resonance Spectroscopy
  • Molecular Conformation
  • Plant Bark / chemistry
  • Plant Stems / chemistry
  • Reactive Oxygen Species / chemistry
  • Spectrometry, Mass, Fast Atom Bombardment
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet

Substances

  • Antioxidants
  • Chromans
  • Flavones
  • Free Radical Scavengers
  • Reactive Oxygen Species
  • daphnogirin A
  • daphnogirin B
  • 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
  • Fluorescein