Abstract
Angiogenesis has become a major issue in oncology. Different in vivo angiogenesis assays have been developed in order to better understand fundamental aspects of vascular development or to investigate the effect of therapeutic molecules on blood vessel growth. In this article, we will briefly review the main in vivo angiogenesis assays relevant to oncology and discuss their advantages and disadvantages.
MeSH terms
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Animals
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Blood Vessels / embryology
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Chick Embryo
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Chorioallantoic Membrane / blood supply
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Collagen
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Corneal Neovascularization / etiology
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Drug Combinations
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Ear, External / blood supply
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Laminin
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Models, Animal
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Neoplasms / blood supply
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Neovascularization, Pathologic / diagnosis
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Neovascularization, Pathologic / embryology*
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Neovascularization, Physiologic / physiology*
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Proteoglycans
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Rabbits
Substances
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Drug Combinations
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Laminin
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Proteoglycans
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matrigel
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Collagen