Fetal death certificates as a source of surveillance data for stillbirths with birth defects

Public Health Rep. 2007 Sep-Oct;122(5):664-9. doi: 10.1177/003335490712200514.

Abstract

Objective: We assessed fetal death certificates (FDCs) as a source of surveillance for stillbirths with birth defects by linkage with data from the Metropolitan Atlanta Congenital Defects Program (MACDP), a population-based birth defects surveillance system.

Methods: Stillbirths with defects in MACDP were identified from 1994 through 2002 and linked to FDCs. Sensitivity of FDCs for capturing stillbirths with defects was estimated, and predictors for a case being reported were assessed. Concordance for selected variables from each data source was evaluated. RESILTS: Two hundred twenty-four of 257 stillbirths with birth defects in MACDP were linked to an FDC (linkage rate = 87.2%; 95% confidence interval [CI] 82.4, 91.0). Stillbirths of non-Hispanic black and Hispanic/other mothers were more likely to be issued an FDC (odds ratio [OR] = 5.6 [95% CI 1.9, 17.0] and 14.0 [95% CI 1.7, 114.0], respectively). Cases undergoing autopsy were more likely to be issued an FDC (OR = 3.2; 95% CI 1.1, 8.7). Performance of an amniocentesis was poorly recorded on FDCs. The sensitivity and positive predictive value of FDCs for selected classes of defects ranged from 10% to 70% and 25% to 93%, respectively.

Conclusions: Compared to FDCs, MACDP's active case identification improves the ascertainment of stillbirths with birth defects and the quality of certain recorded data.

MeSH terms

  • Congenital Abnormalities / epidemiology*
  • Death Certificates*
  • Female
  • Fetal Death / epidemiology*
  • Georgia / epidemiology
  • Humans
  • Infant, Newborn
  • Population Surveillance / methods*
  • Pregnancy
  • Stillbirth / epidemiology*
  • United States / epidemiology