Intranasal desmopressin (Octim): a safe and efficacious treatment option for children with bleeding disorders

Haemophilia. 2007 Sep;13(5):548-51. doi: 10.1111/j.1365-2516.2007.01519.x.

Abstract

Desmopressin (1-deamino-8-D-arginine vasopressin (DDAVP)) has been shown to be an effective treatment option when administered both intravenously [1,2] and subcutaneously [3] to children with inherited bleeding disorders. We demonstrate here, both the efficacy and acceptability of a new intranasal DDAVP preparation, providing a cost effective treatment with good outcomes for children with bleed disorders.

MeSH terms

  • Administration, Intranasal
  • Adolescent
  • Child
  • Cohort Studies
  • Deamino Arginine Vasopressin / administration & dosage*
  • Deamino Arginine Vasopressin / adverse effects
  • Dose-Response Relationship, Drug
  • Female
  • Hemophilia A / drug therapy*
  • Hemorrhage / etiology
  • Hemorrhage / prevention & control*
  • Hemostatics / administration & dosage*
  • Hemostatics / adverse effects
  • Humans
  • Male
  • Treatment Outcome

Substances

  • Hemostatics
  • Deamino Arginine Vasopressin