Isolated liver perfusion versus hepatic artery infusion with 5-fluorouracil in a rat model; effects on thymidylate synthase

Adv Exp Med Biol. 1991:309A:105-8. doi: 10.1007/978-1-4899-2638-8_23.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Binding Sites
  • Bone Marrow / drug effects
  • Bone Marrow / enzymology
  • Cell Line
  • Colonic Neoplasms / drug therapy*
  • Colonic Neoplasms / enzymology
  • Fluorodeoxyuridylate / metabolism
  • Fluorouracil / administration & dosage*
  • Fluorouracil / pharmacology
  • Fluorouracil / therapeutic use
  • Infusions, Intra-Arterial
  • Liver / drug effects
  • Liver / enzymology*
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / enzymology
  • Liver Neoplasms / secondary*
  • Perfusion
  • Rats
  • Thymidylate Synthase / metabolism*

Substances

  • Fluorodeoxyuridylate
  • Thymidylate Synthase
  • Fluorouracil