An organocatalytic approach to the core of eunicellin

Ryan Gilmour; Timothy J Prior; Jonathan W Burton; Andrew B Holmes

doi:10.1039/b709322e

An organocatalytic approach to the core of eunicellin

Chem Commun (Camb). 2007 Oct 14:(38):3954-6. doi: 10.1039/b709322e. Epub 2007 Aug 20.

Authors

Ryan Gilmour¹, Timothy J Prior, Jonathan W Burton, Andrew B Holmes

Affiliation

¹ Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UKCB2 1EW.

PMID: 17896044
DOI: 10.1039/b709322e

Abstract

A stereocontrolled synthesis of the core of eunicellin is described featuring a Claisen rearrangement and a diastereoselective organocatalytic Diels-Alder reaction as the key steps.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Diterpenes / chemical synthesis*
Diterpenes / chemistry
Molecular Conformation

Substances

Diterpenes
eunicellin