Scaffold hopping by "fuzzy" pharmacophores and its application to RNA targets

Chembiochem. 2007 Nov 5;8(16):1932-6. doi: 10.1002/cbic.200700195.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acepromazine / chemistry*
  • Acepromazine / pharmacology
  • Anti-HIV Agents / chemistry*
  • Anti-HIV Agents / pharmacology
  • Binding Sites
  • Computational Biology / methods
  • Drug Design
  • Fluorescence Resonance Energy Transfer
  • Ligands
  • Models, Molecular
  • Molecular Structure
  • RNA, Viral / chemistry*
  • RNA, Viral / drug effects
  • Software
  • Stereoisomerism
  • Structure-Activity Relationship
  • tat Gene Products, Human Immunodeficiency Virus / antagonists & inhibitors*
  • tat Gene Products, Human Immunodeficiency Virus / chemistry

Substances

  • Anti-HIV Agents
  • Ligands
  • RNA, Viral
  • tat Gene Products, Human Immunodeficiency Virus
  • Acepromazine