Abstract
A single-center cross sectional evaluation of beta-2 micro-globinuria as a marker of proximal renal tubule damage in 92 HIV-infected children showed that tenofovir treatment was significantly associated with very high abnormal values. In view of the very long duration of treatments for HIV infection, their possible consequences for the child's growing body should be carefully evaluated.
MeSH terms
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Adenine / adverse effects
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Adenine / analogs & derivatives*
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Adolescent
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Adult
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Child
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Child, Preschool
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Cross-Sectional Studies
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Female
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HIV Infections / complications*
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HIV Infections / drug therapy*
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Humans
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Male
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Organophosphonates / adverse effects*
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Proteinuria*
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Reverse Transcriptase Inhibitors / adverse effects
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Tenofovir
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Urine / chemistry*
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beta 2-Microglobulin / analysis*
Substances
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Organophosphonates
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Reverse Transcriptase Inhibitors
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beta 2-Microglobulin
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Tenofovir
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Adenine