Abstract
Graph theoretical concepts are useful for the description and analysis of interactions and relationships in biological systems. We give a brief introduction into some of the concepts and their areas of application in molecular biology. We discuss software that is available through the Bioconductor project and present a simple example application to the integration of a protein-protein interaction and a co-expression network.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Algorithms
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Computational Biology / methods*
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Computational Biology / trends*
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Computer Graphics*
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Computer Simulation
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Gene Expression Profiling / methods*
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Gene Expression Regulation / physiology
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Models, Biological*
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Oligonucleotide Array Sequence Analysis / methods
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Proteome / metabolism*
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Signal Transduction / physiology*
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Transcription, Genetic / physiology